1'-hydroxy Midazolam (Synonyms: Ro 21-6347) |
Catalog No.GC41995 |
Principal métabolite de l'anesthésique, le midazolam.
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Cas No.: 59468-90-5
Sample solution is provided at 25 µL, 10mM.
1’-hydroxy Midazolam is the major metabolite of the anesthetic, midazolam. It is produced rapidly by the actions of hepatic cytochrome P450 3A and has been shown to be equipotent to midazolam.[1]
Reference:
[1]. Perloff, M.D., Von Moltke, L.L., Court, M.H., et al. Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms. Journal of Pharmacology and Experimental Therapeutics 292(2), 618-628 (2016).
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