4-Hydroxy-2-methylbenzenesulfonic acid ammonium |
| Catalog No.GC60025 |
L'ammonium de l'acide 4-hydroxy-2-méthylbenzènesulfonique est une impureté de Policresulen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2742982-16-5
Sample solution is provided at 25 µL, 10mM.
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4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].
[1]. Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.
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