AVE5688 |
Catalog No.GC31627 |
AVE5688 est un inhibiteur de la glycogène phosphorylase (GP), avec des IC50 de 430 nM et 915 nM et des Kd de 170 nM et 530 nM pour la glycogène phosphorylase musculaire de lapin (rmGPb et rmGPa, respectivement) ; AVE5688 peut être utilisé pour la recherche sur le diabète de type 2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 613260-13-2
Sample solution is provided at 25 µL, 10mM.
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively)[1].
[1]. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.
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