Calcineurin substrate |
| Catalog No.GC30990 |
Le substrat de la calcineurine est un peptide de la sous-unité régulatrice RII de la protéine kinase dépendante de l'AMPc.
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Cas No.: 113873-67-9
Sample solution is provided at 25 µL, 10mM.
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Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay.
Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves[1].
[1]. Crabtree GR, et al. Calcium, calcineurin, and the control of transcription. J Biol Chem. 2001 Jan 26;276(4):2313-6.
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