CB-7921220 |
| Catalog No.GC18571 |
CB-7921220 est un inhibiteur de l'adénylate cyclase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 115453-99-1
Sample solution is provided at 25 µL, 10mM.
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CB-7921220 is an adenylate cyclase inhibitor.
CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6[1].
References:
[1]. Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
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