Folipastatin |
Catalog No.GC43695 |
La folipastatine est un puissant inhibiteur de la phospholipase A2 avec une IC50 de 39 μM.
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Cas No.: 139959-71-0
Sample solution is provided at 25 µL, 10mM.
Folipastatin is a fungal metabolite produced by A. unguis and an inhibitor of phospholipase A2 (PLA2; IC50 = 39 μM). It inhibits release of arachidonic acid from rat polymorphonuclear leukocytes (IC50 = 24 μM). Folipistatin also inhibits radioligand binding to L-type calcium channels in porcine heart membranes (IC50 = 0.39 μM) but has no effect on contraction of taenia (IC50 = >100 μM).
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