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Carbodine

Catalog No.GC35606

La carbodine (cytidine carbocyclique) est un agent antiviral À large spectre actif contre les virus À ADN, les virus À ARN (+), les virus À (-)ARN, les virus paramyxo, rhabdo et (+/-)ARN, cible la CTP synthétase qui convertit UTP en CTP.

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Carbodine Chemical Structure

Cas No.: 71184-20-8

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro[1][2].

[1]. De Clercq E, et al. Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine. Biochem Pharmacol. 1990 Jan 15;39(2):319-25. [2]. Shannon WM, et al. Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses. Antimicrob Agents Chemother. 1981 Dec;20(6):769-76.

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