GW284543 (Synonyms: UNC10225170) |
Catalog No.GC36199 |
GW284543 (UNC10225170) est un inhibiteur sélectif de MEK5. GW284543 réduit pERK5 et diminue la protéine MYC endogène.
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Cas No.: 790186-68-4
Sample solution is provided at 25 µL, 10mM.
GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 (UNC10225170) reduces pERK5, and decreases endogenous MYC protein[1]. MEK5
[1]. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7.
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