LSD1-IN-5 |
Catalog No.GC36484 |
LSD1-IN-5 (composé 4e) est un inhibiteur puissant et réversible de la déméthylase spécifique de la lysine 1 (LSD1), avec une IC50 de 121 nM. LSD1-IN-5 augmente la Lys4 diméthylée de l'histone H3, ne montre aucun effet sur l'expression de LSD1.
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Cas No.: 2035912-55-9
Sample solution is provided at 25 µL, 10mM.
LSD1-IN-5 (Compound 4e) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 121 nM (LSD1)[1]
[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
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