Tyrphostin AG30 |
| Catalog No.GC38125 |
La tyrphostine AG30 (AG30) est un inhibiteur puissant et sélectif de la tyrosine kinase EGFR. La tyrphostine AG30 (AG30) inhibe sélectivement l'induction de l'auto-renouvellement par c-ErbB et est capable d'inhiber l'activation de STAT5 par c-ErbB dans les érythroblastes primaires.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 122520-79-0
Sample solution is provided at 25 µL, 10mM.
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Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
[1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. [2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93.
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