BI-167107 |
| Catalog No.GC38378 |
Le BI-167107 est un agoniste complet de haute affinité qui se lie au récepteur β2 adrénergique (β2AR) avec une constante de dissociation Kd de 84 pM.
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Cas No.: 1202235-68-4
Sample solution is provided at 25 µL, 10mM.
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BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM[1].
Compared to other βAR ligands, BI-167107 displays nanomolar affinities and slow off-rates[1].
[1]. Rasmussen SG, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 2011 Jan 13;469(7329):175-80.
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