Accueil>>Signaling Pathways>> Ubiquitination/ Proteasome>> Mitophagy>>GSK2578215A

GSK2578215A

Catalog No.GC18049

GSK2578215A est un inhibiteur puissant et hautement sélectif de LRRK2, qui présente des IC50 d'environ 10 nM contre LRRK2 de type sauvage et le mutant G2019S.

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GSK2578215A Chemical Structure

Cas No.: 1285515-21-0

Taille Prix Stock Qté
10mM (in 1mL DMSO)
34,00 $US
En stock
10mg
47,00 $US
En stock
50mg
176,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GSK2578215A is a potent and highly selective LRRK2 inhibitor, which exhibits IC50s of around 10 nM against both wild-type LRRK2 and the G2019S mutant.

References:
[1]. Reith AD, et al. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5625-9.

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Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

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