GSK2578215A |
Catalog No.GC18049 |
GSK2578215A est un inhibiteur puissant et hautement sélectif de LRRK2, qui présente des IC50 d'environ 10 nM contre LRRK2 de type sauvage et le mutant G2019S.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1285515-21-0
Sample solution is provided at 25 µL, 10mM.
GSK2578215A is a potent and highly selective LRRK2 inhibitor, which exhibits IC50s of around 10 nM against both wild-type LRRK2 and the G2019S mutant.
References:
[1]. Reith AD, et al. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5625-9.
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