(+)-Praeruptorin A |
Catalog No.GC40266 |
(+) - La praeruptorine A est un constituant bioactif principal de Peucedanum praeruptorum (également connu sous le nom de Bai-Hua Qian Hu).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 73069-27-9
Sample solution is provided at 25 µL, 10mM.
(+)-Praeruptorin A is a coumarin derivative originally isolated from P. praeruptorum. It prevents LPS-induced increases in IL-1β and TNF-α in a concentration-dependent manner when used at concentrations ranging from 6.25 to 100 µM and IL-6 at concentrations ranging from 25 to 100 µM. It inhibits potassium chloride-induced contraction of isolated rabbit trachea by 50 and 100% when used at concentrations of 4.8 and 30 µM, respectively. Topical administration of (+)-praeruptorin A (0.3 µmol/cm2) reduces edema by 22% in a croton oil mouse model of inflammation.
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