TNP (Synonyms: IP3K Inhibitor, IP6K Inhibitor) |
| Catalog No.GC17758 |
Le TNP est un inhibiteur perméable aux cellules de IP6K1 et IP3K, avec des valeurs IC50 de 0,55 μM et 10,2 μM pour IP3K, respectivement. Le TNP se lie aux sites de liaison À l'ATP des deux enzymes.
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Cas No.: 519178-28-0
Sample solution is provided at 25 µL, 10mM.
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TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].
References:
[1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.
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