Uric Acid (sodium salt) (Standard) |
Catalog No.GC45126 |
L'acide urique (sel de sodium) (urate monosodique), piégeur de radicaux oxygène, est un antioxydant très important qui aide À maintenir la stabilité de la pression artérielle et du stress antioxydant.
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Cas No.: 1198-77-2
Sample solution is provided at 25 µL, 10mM.
Uric acid is a ubiquitous end product of purine metabolism in humans that is mainly excreted in urine, whereas in other mammals it is further metabolized to allantoin by uricase. The final two steps in its production are catalyzed by xanthine oxidase, which generates superoxide. Uric acid acts as a potent peroxynitrite scavenger and antioxidant. However, high levels of serum uric acid (>120 µg/ml), termed hyperuricemia, are associated with gout, kidney stones, metabolic syndrome, hypertension, renal disease, and cardiovascular disease. Uric acid in the form of monosodium urate crystals has been proposed to trigger interleukin-1β-mediated inflammation by activating the NOD-like receptor protein 3 inflammasome.
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