Vebufloxacin (Flumenique) |
Catalog No.GC33708 |
La vébufloxacine (Flumenique) (Flumenique; OPC7241; DM8966) présente une puissante activité antibactérienne contre les bactéries gram-positives et négatives.
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Cas No.: 79644-90-9
Sample solution is provided at 25 µL, 10mM.
Vebufloxacin (Flumenique; OPC7241; DM8966) exhibits potent antibacterial activity against gram-positive and -negative bacteria.
A series of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids is synthesized and tested for antibacterial activities. Among them, Vebufloxacin (OPC-7241) exhibits potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, and OPC-7251 shows potent activity characteristically against Propionibacterium acnes[1].
[1]. Ishikawa H, et al. Studies on antibacterial agents. I. Synthesis of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids. Chem Pharm Bull (Tokyo). 1989 Aug;37(8):2103-8.
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