RN 1747 |
| Catalog No.GC15346 |
RN 1747 est un agoniste sélectif du membre 4 de la sous-famille V des canaux cationiques potentiels du récepteur transitoire (TRPV4), avec des valeurs d'EC50 de 0,77 μM, 4,0 μM et 4,1 μM pour hTRPV4, mTRPV4 et rTRPV4 respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1024448-59-6
Sample solution is provided at 25 µL, 10mM.
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RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1].
References:
[1]. Vincent F, et al. Identification and characterization of novel TRPV4 modulators. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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