Roxatidine Acetate HCl (Synonyms: HOE 760, TZU-0460) |
| Catalog No.GC10369 |
L'acétate de roxatidine HCl est un antagoniste des récepteurs H2 de l'histamine puissant, sélectif, compétitif et actif par voie orale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 93793-83-0
Sample solution is provided at 25 µL, 10mM.
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Roxatidine Acetate Hydrochloride is a specific and competitive histamin H2 receptor antagonist.Target: Histamin H2 ReceptorRoxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist which, after almost complete oral absorption (greater than 95%), is rapidly converted to its active metabolite, roxatidine, by esterases in the small intestine, plasma and liver. Roxatidine Acetate Hydrochloride is a potent inhibitor of basal and stimulated gastric acid secretion in animals and humans and, like most other H2-receptor antagonists, has no anti-androgenic effects and does not interfere with the hepatic metabolism of other drugs [1, 2].
References:
[1]. Murdoch, D. and D. McTavish, Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs, 1991. 42(2): p. 240-60.
[2]. Pali-Scholl, I. and E. Jensen-Jarolim, Anti-acid medication as a risk factor for food allergy. Allergy, 2011. 66(4): p. 469-77.
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