S 07662 |
| Catalog No.GC50118 |
Constitutive androstane receptor (CAR) inverse agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 883226-64-0
Sample solution is provided at 25 µL, 10mM.
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Inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.
Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID:22044162
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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