Secretin (rat) (Synonyms: Secretin (rat)) |
| Catalog No.GC16381 |
La sécrétine (rat) est un peptide 27-aa, agit sur le récepteur de la sécrétine, améliore la sécrétion de bicarbonate, d'enzymes et de K+ du pancréas.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 121028-49-7
Sample solution is provided at 25 µL, 10mM.
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Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.
Secretin (33-59), rat inhibits adrenocorticotropic hormone (ACTH) release, and selectively suppresses the glucocorticoid response to ACTH of dispersed zona fasciculata-reticularis (ZF/R) cells[1]. Secretin retrograde messenger to facilitate GABA transmission in the rat cerebellum[2].
References:
[1]. Nussdorfer GG, et al. Secretin, glucagon, gastric inhibitory polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus- pituitary-adrenal axis. Peptides. 2000 Feb;21(2):309-24.
[2]. Ng SS, et al. Secretin as a neuropeptide. Mol Neurobiol. 2002 Aug;26(1):97-107.
| Cas No. | 121028-49-7 | SDF | |
| Synonymes | Secretin (rat) | ||
| Canonical SMILES | CC(C[C@@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N | ||
| Formula | C129H216N42O42 | M.Wt | 3027.38 |
| Solubility | Soluble in Water | Storage | Desiccate at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 0.3303 mL | 1.6516 mL | 3.3032 mL |
| 5 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL |
| 10 mM | 0.033 mL | 0.1652 mL | 0.3303 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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