Sp-Adenosine-5'-O-(1-thiotriphosphate) (sodium salt) |
| Catalog No.GC90896 |
Un isomère de ATP-α-S et un agoniste du récepteur P2Y1.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S) is an isomer of the sulfur-containing nucleotide derivative ATP-α-S and an agonist of the purinergic P2Y1 receptor.1 It increases calcium mobilization in HEK293 cells expressing the P2Y1 receptor (EC50 = 9.4 nM for the human receptor). Sp-ATP-α-S inhibits ADP-induced aggregation of isolated human platelets (Ki = 4 μM).2 It induces relaxation of carbamoylcholine-preconstricted guinea pig taenia coli (EC50 = 426 nM).3
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