ST-1006 |
| Catalog No.GC70497 |
ST-1006 est un agoniste puissant des récepteurs H4 de l'Histamine avec un PKI de 7,94.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1196994-11-2
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
ST-1006 (10 μM) is a potent inducer of basophil migration and induces migration of basophils[2].
ST-1006 (0-100 μM) suppresses FceRImediated basophil activation and reduces the CD63 and CD203c expression levels on FceRI-activated basophils[2].
ST-1006 (1-100 mg/kg; s.c.; Male CD-1 mice) has anti-inflammatory effect and displays an antipruritic effect[1].
References:
[1]. Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397.
[2]. Mommert S, et, al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016 Sep;71(9):1264-73.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *