Sucralose |
| Catalog No.GC10278 |
Le sucralose(E955; trichlorosaccharose) est un édulcorant artificiel non nutritif et un substitut du sucre. Le sucralose peut activer une réponse de jeÛne neuronal conservée et exerce ainsi un effet stimulant l'appétit chez les rongeurs.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56038-13-2
Sample solution is provided at 25 µL, 10mM.
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Sucralose is an intense organochlorine artificial sweetener.
The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues[1].
References:
[1]. M S, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016 Jan;22(1):7-17.
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