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SuO-Glu-Val-Cit-PAB-MMAE

Catalog No.GC63859

SuO-Glu-Val-Cit-PAB-MMAE consiste en un lieur ADC clivable (SuO-Glu-Val-Cit-PAB) et un puissant inhibiteur de la tubuline (MMAE). SuO-Glu-Val-Cit-PAB-MMAE peut être utilisé dans la synthèse de conjugués anticorps-médicament (ADC).

Products are for research use only. Not for human use. We do not sell to patients.

SuO-Glu-Val-Cit-PAB-MMAE Chemical Structure

Cas No.: 1895916-24-1

Taille Prix Stock Qté
1mg
315,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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Review for SuO-Glu-Val-Cit-PAB-MMAE

Average Rating: 5 ★★★★★ (Based on Reviews and 2 reference(s) in Google Scholar.)

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