TCO-PEG4-biotin |
| Catalog No.GC64374 |
TCO-PEG4-biotine est un lieur PROTAC À base de PEG qui peut être utilisé dans la synthèse des PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2183440-30-2
Sample solution is provided at 25 µL, 10mM.
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TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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