Tertiapin LQ (trifluoroacetate salt) |
Catalog No.GC90627 |
Un dérivé peptidique de la tertiapine
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Sample solution is provided at 25 µL, 10mM.
Tertiapin LQ is a peptide derivative of the honeybee venom peptide tertiapin and an inhibitor of inwardly rectifying potassium (Kir) channels.1,2 It inhibits heteromultimeric potassium channels composed of G protein-activated inward rectifier potassium channel 1 (GIRK1) and GIRK4, also known as Kir3.1 and Kir3.4, respectively, as well as the inward-rectifier potassium channel 1 (Kir1.1). In vivo, tertiapin LQ suppresses the Purkinje cell pause response to a conditional stimulus in ferrets. 2
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