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Teslexivir (BTA074) (Synonyms: BTA074; AP 611074)

Catalog No.GC32298

Teslexivir (BTA074) (BTA074) est un agent antiviral puissant.

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Teslexivir (BTA074) Chemical Structure

Cas No.: 1075798-37-6

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Sample solution is provided at 25 µL, 10mM.

Description of Teslexivir (BTA074)

Teslexivir (BTA074; AP 611074) is a topical antiviral agent that is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an interaction that is a necessary step for Human Papilloma Virus (HPV) 6 and 11 DNA replication and thus viral production.

[1]. CAS Group Announces Glass Lewis Recommendation That Aviragen Stockholders Vote AGAINST Merger and Emphasizes Value of Teslexivir (BTA074) Program. Jan 31, 2018.

Chemical Properties of Teslexivir (BTA074)

Cas No. 1075798-37-6 SDF
Synonymes BTA074; AP 611074
Canonical SMILES O=C(CC1=CC(OC)=C(C(O)=O)C=C1Br)NN(C2=CC=C(CC3=CC=CC=C3)C=C2)C4=C(N5CCCCC5)C=CC=C4C
Formula C35H36BrN3O4 M.Wt 642.58
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Teslexivir (BTA074)

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1 mg 5 mg 10 mg
1 mM 1.5562 mL 7.7811 mL 15.5623 mL
5 mM 0.3112 mL 1.5562 mL 3.1125 mL
10 mM 0.1556 mL 0.7781 mL 1.5562 mL
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In vivo Formulation Calculator (Clear solution) of Teslexivir (BTA074)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for Teslexivir (BTA074)

Average Rating: 5 ★★★★★ (Based on Reviews and 16 reference(s) in Google Scholar.)

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