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Thiolactomycin

Catalog No.GC70531

Thiolactomycin est un antibiotique.

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Thiolactomycin Chemical Structure

Cas No.: 82079-32-1

Taille Prix Stock Qté
1 mg
558,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids.

References:
[1]. Price AC, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9.
[2]. Slayden RA, et al. Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis. Antimicrob Agents Chemother. 1996 Dec;40(12):2813-9.

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