Toremifene-d6 (Synonyms: Z-Toremifene-d6; NK 622-d6 free base; FC-1157a-d6 free base) |
Catalog No.GC48188 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
Toremifene-d6 is intended for use as an internal standard for the quantification of toremifene by GC- or LC-MS. Toremifene is an orally bioavailable selective estrogen receptor modulator (SERM) that evokes tissue-dependent effects similar to that of tamoxifen .1 It has been shown to block estrogen-stimulated growth of MCF-7 breast cancer cells grown in tissue culture, to inhibit ovariectomy-induced bone loss in rats, and to stimulate endometrial growth similar to that of tamoxifen.1
1.Goldstein, S.R., Siddhanti, S., Ciaccia, A.V., et al.A pharmacological review of selective oestrogen receptor modulatorsHum. Reprod. Update6(3)212-224(2000)
Average Rating: 5
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