Trepibutone |
| Catalog No.GC70286 |
Trepibutone (AA 149) augmente la sécrétion de bile et de suc pancréatique, et accélère la flaccidité du muscle lisse dans le tractus gastro-intestinal.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 41826-92-0
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Trepibutone (1-1000 μM) markedly relaxes the sphincter of Oddi and duodenum[1].
Trepibutone (1-20 mg/kg; i.v. once) dose-dependently increases bile flow[2].
Trepibutone (10 mg/kg; i.v. 3 h after 14C-erythritol injection) stimulates canalicular bile formation without enhancement of water secretion and inhibition of bile reabsorption in the biliary ductules and ducts[2].
References:
[1]. Hiroshi Saton, et al. RELAXING ACTION OF TREPIBUTONE (AA-149) ON THE ISOLATED SPHINCTER OF ODDI AND SMALL INTESTINE OF RABBITS. The Japanese Journal of Pharmacology. 1981.
[2]. Satoh H, et al. A possible mechanism of choleretic action of 3-(2,4,5-triethoxybenzoyl)-propionic acid (AA-149) in dogs. Eur J Pharmacol. 1978 Mar 1;48(1):125-32.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *