UCB-6876 |
| Catalog No.GC71380 |
UCB-6876 est un inhibiteur de TNFα et se lie à la forme de cristal asymétrique du trimer de TNF (KD = 22 μM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 637324-45-9
Sample solution is provided at 25 µL, 10mM.
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References:
[1]. Eguida M, et al. Unexpected similarity between HIV-1 reverse transcriptase and tumor necrosis factor binding sites revealed by computer vision. J Cheminform. 2021 Nov 23;13(1):90.
[2]. O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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