VUT-MK142 |
| Catalog No.GC62324 |
VUT-MK142 est un nouvel agent synthétique cardiomyogénique puissant favorisant la différenciation du mésoderme pré-cardiaque en cardiomyocytes, qui peut être utile pour différencier les cellules souches en cardiomyocytes pour la réparation cardiaque .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1313491-22-3
Sample solution is provided at 25 µL, 10mM.
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VUT-MK142 is a potent new cardiomyogenic synthetic agent promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair[1].
VUT-MK142 possesses promising cardiomyogenic effects on various cell types. VUT-MK142 shows a remarkable effect on both P19 and C2C12 cells. Compared to CgC, VUT-MK142-treatment leads to a markedly stronger up-regulation of the expression of ANF[1].VUT-MK142 (1 μM, 7 day treatment) significantly (p < 0.05) increases the luciferase signal by 3.1 ± 0.3 luciferase (n = 5)-fold in P19 cells[1].
[1]. Moumita Koley, et al. VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes. Medchemcomm. 2013 Aug 1;4(8):1189-1195.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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