YQ128 |
Catalog No.GC39311 |
YQ128 est un inhibiteur puissant et sélectif de l'inflammasome NLRP3 (récepteur de type NOD P3) de deuxième génération avec une IC50 de 0,30 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2454246-18-3
Sample solution is provided at 25 µL, 10mM.
YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM. YQ128 significantly and selectively suppresses the production of IL-1β, but not TNF-α, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity[1].
[1]. Jiang Y, et al. Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization. J Med Chem. 2019 Oct 31.
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(Based on Reviews and 2 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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