Z-(L-Arg)-AMC (hydrochloride) (Synonyms: Bz-Arg-AMC, N-benzoxy-L-Arg-7-amido-4-methylcoumarin, N-benzoyl-L-Arg-AMC, Z-Arg(HCl)AMC) |
| Catalog No.GC48471 |
Le Z-(L-Arg)-AMC (chlorhydrate) est un substrat fluorogène pour la trypsine et la papaÏne.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70375-22-3
Sample solution is provided at 25 µL, 10mM.
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Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2 Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
1.Zimmerman, M., Ashe, B., Yurewicz, E.C., et al.Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substratesAnal. Biochem.78(1)47-51(1977) 2.Brindley, P.J., Kalinna, B.H., Dalton, J.P., et al.Proteolytic degradation of host hemoglobin by schistosomesMol. Biochem. Parasitol.89(1)1-9(1997)
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