Boc-Asp(OBzl)-chloromethylketone |
Catalog No.GA20905 |
Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without affecting tumor necrosis factor processing.
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Cas No.: 172702-58-8
Sample solution is provided at 25 µL, 10mM.
Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without
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