α-Synuclein (45-54) (human) |
Catalog No.GA23997 |
Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson's disease (PD). Most early onset mutations are located between residues 46-53. The sequence of α-synuclein (45-54) was used by Cheruvara and coworkers as a template for a peptide library. The authors isolated a 10-residue peptide antagonist that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
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Cas No.: 2243206-98-4
Sample solution is provided at 25 µL, 10mM.
Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson's disease (PD). Most early onset mutations are located between residues 46-53. The sequence of α-synuclein (45-54) was used by Cheruvara and cowo
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