Gabapentin lactam (Synonyms: 4,4-Pentamethylene-2-pyrrolidone) |
| Catalog No.GB40202 |
Gabapentin lactam (CAS 64744-50-9) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease. Displays neurotrophic effects, enhancing the formation of dendritic filopodia and inducing a network of F-actin-containing neurites in cultured hippocampal neurons. Promotes the survival of cultured central nervous system neurons possibly by opening mitochondrial KATP channels. Displays neuroprotective effects in a rat model of acute retinal ischemia.
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Cas No.: 64744-50-9
Sample solution is provided at 25 µL, 10mM.
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Gabapentin lactam (CAS 64744-50-9) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease. Displays neurotrophic effects, enhancing the formation of dendritic filopodia and inducing a network of F-actin-containing neurites in cultured hippocampal neurons. Promotes the survival of cultured central nervous system neurons possibly by opening mitochondrial KATP channels. Displays neuroprotective effects in a rat model of acute retinal ischemia.
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