ASP6432 |
| Catalog No.GC35409 |
ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1282549-08-9
Sample solution is provided at 25 µL, 10mM.
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ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively[1]. IC50: 11 nM (human LPA1), 30 nM (rat LPA1)[1]
ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells[1].
[1]. Sakamoto K, et al. Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation. J Pharmacol Exp Ther. 2018 Aug;366(2):390-396.
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