diABZI STING agonist-1 |
| Catalog No.GC35853 |
diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138299-33-7
Sample solution is provided at 25 µL, 10mM.
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diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. STING[1].
diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.
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