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TAS4464 hydrochloride

Catalog No.GC37743

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.

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TAS4464 hydrochloride Chemical Structure

Cas No.: 1848959-11-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. IC50:0.955 nM (NAE)[1]

[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.

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