1-Phenyl-2-pyrrolidone |
Catalog No.GD20040 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4641-57-0
Sample solution is provided at 25 µL, 10mM.
1-Phenyl-2-pyrrolidinone (1-Phenylpyrrolidin-2-one) is a phenyl analogue of GABA with sedative effect, decreasing the exploratory behavior of rats at 50-100 mg/kg (i.v.). 1-Phenyl-2-pyrrolidinone also has been proved to inhibit emotional reactions in dogs and cats. 1-Phenyl-2-pyrrolidinone induces decreases in the pressor reaction to emotional stress without accompanied by normalization of the function of baroreceptor reflexes.
[1]. Patkina N, et al. Some psychotropic effects of phenibut and phenylpyrrolidone. Trudy Volgogradskogo Gosudarstvennogo Meditsinskogo Instituta (1979), 31(3), 63-6.
[2]. Kovalev GV, et al. Effect of 纬-aminobutyric acid derivatives on baroreceptor reflexes in nonanesthetized animals. Russian. 1980, (VINITI 1311-80), 10 pp.
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