4'-Hydroxy-2，4-dimethoxychalcone |
| Catalog No.GF24950 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 151135-64-7
Sample solution is provided at 25 µL, 10mM.
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4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 渭M) and W2 (IC50=4.8 渭M)[1].
4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng鈥/mL in four- to five-week-old ICR mice[1].
[1]. Clare E Gutteridge, et al. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Pharmacology. 2011;87(1-2):96-104.
[2]. Qing-An Zheng, et al. Flavonoids from the Resin of Dracaena cochinchinensis. Helvetica Chimica Acta, 87(5), 1167鈥?171.
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