4，4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2，6-dione |
| Catalog No.GF27697 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 83928-76-1
Sample solution is provided at 25 µL, 10mM.
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Gepirone (0-3 mg/kg for intraperitoneal injection) interacts with progesterone at 5-HT1A receptors to reduce lordosis behavior in female rats treated with estradiol benzoate and progesterone[1].
Gepirone (10, 15 mg/kg for subcutaneous injection, 2, 7, or 14 days) activates the normosensitive postsynaptic 5-HT1A receptor in Male Sprague-Dawley rats[2].
[1]. Mendelson SD, et al. Effects of 5-HT1A selective anxiolytics on lordosis behavior: interactions with progesterone. Eur J Pharmacol. 1986 Dec 16;132(2-3):323-6.
[2]. Blier P, et al. Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse. 1987;1(5):470-80.
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