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GRL0617

Catalog No.GC39172

A SARS-CoV and SARS-CoV-2 PLpro inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

GRL0617 Chemical Structure

Cas No.: 1093070-16-6

Size Price Stock Qty
10mM (in 1mL DMSO)
$270.00
In stock
10mM (in 1mL DMSO)
$270.00
In stock
5mg
$245.00
In stock
10mg
$455.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro)/deubiquitinase, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM[1].

[1]. Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.

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