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ISOX DUAL

Catalog No.GC50267

Dual BRD4 and CBP/p300 bromodomain inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

ISOX DUAL Chemical Structure

Cas No.: 1962928-22-8

Size Price Stock Qty
10 mg
$412.00
In stock
50 mg
$1,733.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Dual CBP/p300 and BRD4 bromodomain inhibitor (IC50 values are 0.65 and 1.5 μM for CBP and BRD4 respectively). Downregulates IL-6, IL-1β and IFN-β in macrophages.

Chekler (2015) Transcriptional profiling of a selective CREB binding protein bromodomain inhibitor highlights therapeutic opportunities. Chem.Biol. 22 1588 PMID:26670081

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Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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