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JAK1-IN-13

Catalog No.GC71475

JAK1-IN-13 (compound 36b) is an orally active, potent and highly selective inhibitor of JAK1 with an IC50 of 0.044 nM.

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JAK1-IN-13 Chemical Structure

Cas No.: 2778330-90-6

Size Price Stock Qty
1 mg
$158.00
In stock
5 mg
$394.00
In stock
10 mg
$630.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
JAK1-IN-13 (compound 36b) is an orally active, potent and highly selective inhibitor of JAK1 with an IC50 of 0.044 nM. JAK1-IN-13 significantly decreases STAT3 phosphorylation.

References:
[1]. Park E, et al. Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis. J Med Chem. 2023 Dec 14;66(23):16342-16363.

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