JMS-17-2 |
| Catalog No.GC65005 |
JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1380392-05-1
Sample solution is provided at 25 µL, 10mM.
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JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 impairs metastatic seeding and colonization of breast cancer cells[1].
JMS-17-2 (10 mg/kg; aministered i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice[1].
[1]. Shen F, et al. Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Mol Cancer Res. 2016 Jun;14(6):518-27.
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