11β-HSD1-IN-11 |
| カタログ番号GC71163 |
11β-HSD1-IN-11（化合物c 1 a）は、ラットおよびヒトに対するIC 50がそれぞれ0.34μMおよび0.13μMである競合する11β−HSD 1阻害剤である。
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Cas No.: 859721-81-6
Sample solution is provided at 25 µL, 10mM.
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A single dose of the 11β-HSD1 inhibitor Merck 544 reduced the overall abundance of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in the rat liver[1].
References:
[1]. Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268.
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