16(R)-Iloprost |
カタログ番号GC40973 |
イロプロストは、カルバプロスタシクリンなどの第一世代安定アナログよりも約10倍強力な効力を持つ、プロスタサイクリン(PGI2)の第二世代構造アナログです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 74843-13-3
Sample solution is provided at 25 µL, 10mM.
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM.
Average Rating: 5
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