ホーム>>Signaling Pathways>> Ox Stress Reagents>> Lipid Peroxidation>>(±)12-HETE

(±)12-HETE (Synonyms: (±)-Hydroxyeicosatetraenoic Acid)

カタログ番号GC40429

(±) 12-LOX 触媒を使用したアラキドン酸の主要な代謝産物である 12-HETE は、用量依存的に細胞アポトーシスを阻害します。

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(±)12-HETE 化学構造

Cas No.: 71030-37-0

サイズ 価格 在庫数 個数
25μg
$100.00
在庫あり
50μg
$188.00
在庫あり
100μg
$358.00
在庫あり
250μg
$795.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 2 publications

Description Chemical Properties Quality Control Product Documents Related Products

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers . It aggregates neutrophils with an EC50 value of 40 nM.[1] 

Reference:
[1]. O'Flaherty, J.T., Thomas, M.J., Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).

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